The same vaccine that is used against true smallpox is effective against Mpox / ‘monkeypox’. Vaccination is regulated differently in the federal states (see Where can I get vaccinated?). The vaccination offers a high level of protection against infection and also greatly reduces the risk of a severe course of the disease if infection does occur.  Deutsche Aidshilfe has summarised the most important information on vaccination against Mpox in a question and answer format (FAQs). According to the current state of knowledge (August 2024), the information also applies to variant (‘clade’) 1b.